Randomized trials and allocation concealment

A great example of problems with a randomization scheme for a clinical trial - "Reliable evidence is the best medicine," Howard Brody, The Grand Rapids Press


More on allocation concealment:

- Schulz KF, Grimes DA. Allocation concealment in randomised trials: defending against deciphering. Lancet. 2002 Feb 16;359(9306):614-8.

- Schulz KF. Assessing allocation concealment and blinding in randomised controlled trials: why bother?, Evidence-Based Medicine 2000; 5:36-38

- CONSORT statement: allocation concealment example

-Forder PM, Gebski VJ, Keech AC. Allocation concealment and blinding: when ignorance is bliss. MJA 2005; 182 (2): 87-89

- Beller EM, Gebski V, Keech AC. Randomisation in clinical trials. MJA 2002 177 (10): 565-567.

and a study exploring how allocation concealment is reported in clinical trial reports: Hewitt C, Hahn S, Torgerson DJ, Watson J, Bland JM. Adequacy and reporting of allocation concealment: review of recent trials published in four general medical journals. BMJ. 2005 May 7;330(7499):1057-8.