Thursday, May 25, 2006

Searching the clinical adverse effects literature

Golder SP, McIntosh HM, Loke YK. Identifying systematic reviews of the adverse effects of health care interventions. BMC Med Res Methodol 2006 May 8;6(1):22

This recent study published in BMC Medical Research Methodology explores the challenges of constructing one catch-all search strategy for identifying systematic reviews of adverse effects of healthcare interventions.

Interesting that even in these relatively small databases, with a topic that seems fairly well-defined, it was difficult to construct strategies that were precise and sensitive;

The authors conclude that hand searching DARE and Cochrane, the 2 resources that were the focus of this work, is the only way to be certain that you've identified all relevant items.


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